What is a common/multifactorial disease?

Multifactorial diseases are common conditions (i.e., hypertension, coronary heart disease and diabetes) that are caused by multiple factors, including genes and external factors, like the environment, diet and lifestyle.

Such diseases are the result of interaction between multiple genetic and external factors that lead to a family predisposition to the disease, without a clear Mendelian inheritance pattern (i.e., classical genetic).

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